Chapter 12 The Cell Cycle p. 215

·        Cell division

·        Cell cycle

Cell division functions in reproduction, growth, and repair p. 215

·        Read

Cell division distributes identical sets of chromosomes to daughter cells p. 216

·        Genome

·        Chromosomes

·        Somatic cells (number of chromosomes)

·        Gametes (number of chromosomes)

·        DNA-protein complex

·        Chromatin

·        Sister chromatids

·        Centromere

·        Figure 12.3 p. 217

·        Mitosis

·        Cytokinesis

·        Meiosis

The Mitotic Cell Cycle p. 217

·        Read

 

The mitotic phase alternates with interphase in the cell cycle p. 217

·        Mitotic phase

·        The cell cycle Figure 12.4 p. 217

·        Interphase

·        G₁ phase

·        S phase

·        G₂ phase

·        G₀ phase

·        You will need to know the different phases  see pages 218-219

·        Interphase

·        Prophase

·        Metaphase

·        Anaphase

·        Telophase

The mitotic spindle distributes chromosomes to daughter cells p. 220

·        Mitotic spindle

·        Figure 12.6 p. 220

·        Centrosome

·        Kinetochore

·        Metaphase plate

Cytokinesis divides the cytoplasm p. 221

·        Cleavage

·        Cleavage furrow

·        Figure 12.8 p. 222

·        Cell plate

·        Figure 12. 8 p. 222

·        Mitosis in a plant cell Figure 12.9 p. 223

Mitosis in eukaryotes may have evolved from binary fission in bacteria p. 223

·        Binary fission (steps/process)

 

·        Figure 12.10 p. 224

 

Regulation of the cell cycle p. 224

·        Read

 

 

A molecular control system drives the cell cycle p. 224

·        Cell cycle control system

·        Figure 12.13 p. 226

Cell cycle checkpoints p. 226

·        What and where are checkpoints?

 

 

 

The cell cycle clock: cyclins and cyclin-dependent kinases p. 226

·        Protein kinases

·        Cyclin

·        Cyclin-dependent kinases or Cdks

·        MPF (maturation-promoting factor)

·        Figure 12.14 p. 227

Internal and external cues help regulate the cell cycle p. 227

·        Growth factors

§         Figure 12.15 p. 228

·        PDGF (platelet-derived growth factor)

·        Density-dependent inhibition

§         Figure 12.16 p. 229

·        Anchorage dependence

·        Substratum

 

Cancer cells have escaped from cell cycle controls p. 228

·        What are the differences between normal cells and cancer cells?

·        Transformation

·        Tumor

·        Benign tumor

·        Malignant tumor

·        Metastasis

·        Figure 12.17 p. 229

 

Self-quiz questions p. 230